Pittsburgh Surgical Outcomes Research Center
Transforming the conduct of clinical research

Trauma/Acute Care Research

Sepsis restructures immune cells

Each year, at least 1.7 million Americans develop sepsis (previously ‘severe sepsis’), of which 270,000 will die. Globally sepsis afflicts 19 million people and incurs 5 million deaths. In the US, it is present in 6% of adult hospitalizations and causes 1 in 3 in-hospital deaths. With a case fatality rate of 15.6%, it is the 10th leading cause of death.

Light and Critical Illness

A translational project using both murine models and human clinical interventional trials to explore the biological and clinical effects (e.g., organ injury, mortality) of light spectral therapy for the treatment of sepsis and traumatic.