The main goal of the study is to provide accurate estimates of the one-, three-, and five-year benefits and risks of the three most common bariatric procedures. This study will involve 10 of PCORnet’s Clinical Data Research Networks (CDRNs) including 53 healthcare organizations and more than 60,000 bariatric patients, with 50 percent gastric bypass, 10 percent gastric banding, and 40 percent sleeve gastrectomy procedures.
The project is the largest study to date to investigate the long-term relationships between bariatric surgery and durable improvements in body weight, hypertension, and renal disease, as well as its association with major operative complications and long-term survival.
This project provides the planning phase to obtain a U01 grant for long-term multi-center study designed to assess the durability and effectiveness of bariatric surgery compared to medical/lifestyle management of T2D in obese patients at seven or more years. The U34 project will focus on harmonization of four randomized trials comparing surgical and medical treatments in Type 2 Diabetes which includes the “Triabetes Study” (A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes).
This is a prospective and longitudinal study that examines the impact of gastric bypass surgery as a treatment for severe obesity by measuring comorbidities, health outcomes, surgical complications and quality of life in both adolescents. The study continues long-term data collection.
This project provides mid-term bridge multi-center extension to four randomized trials comparing surgical and medical treatments in Type 2 Diabetes which includes the “Triabetes Study” (A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes). This study compares outcomes of 3 of the most common bariatric surgical procedures with a comprehensive medical treatment for Type 2 Diabetes in a large cohort of randomized patients (>300) with body mass index between 30 and 40.