Education & Training
- BS, University of Wisconsin-Madison
- PhD, Cornell University Graduate School of Medical Sciences
Representative Publications
Research Interests
The Vodovotz lab carries out studies aimed at obtaining high-dimensional, dynamic data on the etiology and progression of various inflammatory processes and diseases in samples derived from cells, animals, and people; creating computational models based on these data as well as on key principles of immunology, as well as developing novel software tools for data aggregation and analysis; and modulating the inflammatory response in an optimal spatial, temporal, and individual- / disease-specific manner. These studies center on various disease states, especially trauma/hemorrhage, infection, wound healing, and liver failure, as well as the application of computational approaches to regenerative medicine, biomarker discovery, and rational drug/device design. Studies are currently funded by the NIH, Department of Defense, and DARPA. Specific projects, carried out in the context of an interdisciplinary research team with various intramural and extramural collaborators, include:
1. Discovery of novel single-nucleotide polymorphisms (SNPs) associated with altered dynamic networks of systemic inflammation and clinical outcomes in trauma patients
2. Rational reprogramming of wound healing based on engineering principles and computational modeling
3. The impact of age on inflammation and immunity
4. Defining the spatiotemporal spread of inflammation in various experimental models using novel computational methods